Biologics for Eosinophilic Esophagitis

If you have eosinophilic esophagitis (EoE), you’ve probably tried dietary changes and medications. But new treatments, like biologics (biological therapies), offer promising relief. Here’s what you should know about the latest options.

Understanding Biologics for EoE

Biologics are specialized medications designed to target specific pathways involved in inflammation. They are used for various allergic and inflammatory conditions, including EoE.

How Do Biologics Work?

• Target specific molecules involved in inflammation.
• Reduce eosinophils and inflammation in the esophagus.
• Improve swallowing and reduce other symptoms.

Types of Biologics for EoE

• Dupilumab (Dupixent): Currently approved for adults and adolescents, reducing inflammation by targeting specific proteins involved in allergic reactions.
• Other biologics (under investigation): Ongoing clinical trials explore additional biologics that may provide symptom relief.

Benefits of Biologic Treatments

• Significant reduction in swallowing difficulties and food impactions.
• Fewer dietary restrictions.
• Improved overall quality of life.

Are Biologics Right for You?

Biologics might be suitable if:

• Dietary treatments haven’t helped.
• You’re experiencing frequent or severe symptoms.
• Traditional medications aren’t effective enough.

How Are Biologics Administered?

Typically, biologics like Dupilumab are given via injection every few weeks. Your allergist or gastroenterologist will help you understand the process and schedule.

Potential Side Effects

Side effects are generally mild but can include:

• Injection site reactions
• Eye irritation or conjunctivitis
• Respiratory symptoms

FAQs about Biologics for EoE

Are biologics safe?

Yes, they’re considered safe but always discuss risks and benefits with your healthcare provider.

Are biologics a lifelong treatment?

Treatment duration varies based on your response and symptom management. Some individuals may use biologics long-term, while others may adjust treatment over time.

Beyond Biologics: Additional Treatments

• Endoscopic dilation: Helpful for immediate relief of narrowed esophagus sections.
• Dietary management: Often continues alongside biologic therapy for optimal results.

If your current treatment isn’t providing relief, ask your healthcare provider about biologics. These advanced therapies may significantly enhance your symptom control and improve your quality of life.

What are you waiting for?  If you or your child need help controlling allergies or if you think you need testing or treatment or that you might be a good candidate for allergy shots, Dr. Wendt and her team staff at Relieve Allergy, Asthma & Hives would love to help. Call for testing or treatment today!

Call 480-500-1902 or request an appointment at https://relieveallergyaz.com/contact now!  Begin your allergy testing journey with Dr. Wendt at Relieve Allergy in Scottsdale, Arizona—It’s time to take care of yourself!

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DISCLAIMER: This blog is not meant to substitute for medical care by an Allergist-Immunologist nor is it intended to provide medical advice or imply a Physician-Patient relationship with its readers or their family. It is intended to provide guidance, direction, and moral support from someone experienced in testing and treating allergies. This is also not meant to be a “do-it-yourself” manual or a “how to” overcome your allergies. Some of the issues mentioned, whether allergic or look-a-like, can be dangerous or if left unchecked, deadly. Please develop a relationship with a Physician you trust to help you with diagnosis, advice, questions, and treatment regarding your and your family’s medical conditions.