New Biologics for Asthma: Who Should Consider These Advanced Treatments?

For many people, asthma can be controlled with standard inhalers. But what if your asthma remains severe despite taking daily medications? That’s where biologics come in—advanced treatments designed for people with difficult-to-control asthma. But who should consider them, and how do they work? Let’s dive in.

What Are Biologics?

Biologic medications are a newer class of asthma treatment that target specific immune pathways involved in inflammation. Unlike traditional inhalers, biologics are given as injections (or infusions) and work by blocking key molecules that trigger asthma flare-ups.

Who Should Consider Biologics?

Biologics are not for everyone. They are typically recommended for people with:

• Severe Asthma: Symptoms remain uncontrolled despite using high-dose inhaled steroids and other medications.
• Frequent Exacerbations: Multiple asthma attacks requiring steroids, ER visits, or hospitalizations.
• Allergic or Eosinophilic Asthma: High levels of inflammation due to allergens or eosinophils (a type of white blood cell).
• Steroid Dependence: Needing frequent or long-term oral steroids, which have serious side effects.

Types of Biologics for Asthma

There are several FDA-approved biologics for asthma, each targeting different immune pathways:

• Omalizumab (Xolair): Blocks IgE, helpful for allergic asthma.
• Mepolizumab (Nucala), Reslizumab (Cinqair), Benralizumab (Fasenra): Reduce eosinophil levels, effective for eosinophilic asthma.
• Dupilumab (Dupixent): Blocks IL-4 and IL-13, helping both eosinophilic and allergic asthma.
• Tezepelumab (Tezspire): Broadly reduces airway inflammation and is effective for multiple asthma types.

Benefits of Biologic Therapy

Patients who qualify for biologics often see significant improvements:

• Fewer asthma attacks and hospital visits
• Less reliance on oral steroids
• Improved lung function and quality of life
• Reduced airway inflammation

FAQ: Common Questions About Biologics

Q: Are biologics a cure for asthma?
A: No, but they can significantly reduce symptoms and flare-ups.

Q: How often do I need biologic injections?
A: It depends on the medication—some are given every 2 weeks, others once a month or less.

Q: Are there side effects?
A: Most patients tolerate biologics well, but mild injection site reactions or allergic responses can occur.

A Personal Story

One of my patients, John, had suffered from severe asthma for years, relying on frequent steroid bursts. After starting a biologic, his flare-ups dropped dramatically, and he regained control of his life—finally able to play soccer with his kids without gasping for air.

If your asthma remains uncontrolled despite standard treatments, talk to your doctor about whether a biologic might be right for you. Advanced treatments are making a difference, and they could help you breathe easier too!

What are you waiting for?  If you or your child need help controlling allergies or if you think you need testing or treatment or that you might be a good candidate for allergy shots, Dr. Wendt and her team staff at Relieve Allergy, Asthma & Hives would love to help. Call for testing or treatment today!

Call 480-500-1902 or request an appointment at https://relieveallergyaz.com/contact now!  Begin your allergy testing journey with Dr. Wendt at Relieve Allergy in Scottsdale, Arizona—It’s time to take care of yourself!

Learn more about Dr. Wendt and Relieve Allergy Asthma & Hives at www.relieveallergyaz.com or connect with us: https://www.facebook.com/RelieveAllergy/, https://www.linkedin.com/in/julie-wendt/, https://x.com/RelieveAllergy, https://www.instagram.com/relieve_allergy/ or https://www.youtube.com/@JulieWendt-qx7jm.

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Relieve Allergy Asthma & Hives is located near Kierland Commons, 21803 N. Scottsdale Road Ste. 200, and has convenient evening and morning hours to accommodate your schedule. Dr. Wendt is also available for telemedicine appointments as appropriate. Most insurance plans are accepted.

DISCLAIMER: This blog is not meant to substitute for medical care by an Allergist-Immunologist nor is it intended to provide medical advice or imply a Physician-Patient relationship with its readers or their family. It is intended to provide guidance, direction, and moral support from someone experienced in testing and treating allergies. This is also not meant to be a “do-it-yourself” manual or a “how to” overcome your allergies. Some of the issues mentioned, whether allergic or look-a-like, can be dangerous or if left unchecked, deadly. Please develop a relationship with a Physician you trust to help you with diagnosis, advice, questions, and treatment regarding your and your family’s medical conditions.